CORE 2025 is the second annual international conference dedicated to advancing research, development, and innovation in the energy sector and beyond. The conference focuses on non-destructive testing of materials and development of manipulators for the nuclear power industry. The conference also aims to showcase potential applications of the CICRR (Czech International Centre of Research Reactors) infrastructure across academic and industrial fields. The CORE 2025 conference is a continuation of the successful SUSEN conference, which has been organized by the Research Centre Řež since 2018.